Their first award went to actress Mollie Gallagher, who won best Serial Drama Performance for her role as Nina Lucas in the ITV soap.
Their second win came from young actor Jude Riordan, who plays Sam Blakeman on the soap. Riordan was up against Emmerdale's Emile John, Casualty star Olivia D'Lima, Hollyoaks star Rhiannon Clements, and EastEnders actress Rose Ayling-Ellis, who is about to make her debut on Strictly Come Dancing, for the Newcomer award.
And if that wasn't enough, the show scored the hat-trick when they scooped a third award, this time for Serial Drama, beating the likes of Hollyoaks, EastEnders and Emmerdale who won the accolade back in 2020.
The three awards made the ITV soap the biggest winners on the night, with presenting duo Ant and Dec in close second with two awards – for I'm A Celebrity, which won the Bruce Forsyth and Entertainment Award, and Best Presenter, which they won for the 20th time in a row.
Other winners on the night included BBC drama Line of Duty, which won Returning Drama and the Special Recognition award.
The NTAs, which was due to take place in January, aired on Thursday, 9th September, and was hosted by The Masked Singer's Joel Dommett for the first time.