It's safe to say the characters of Big Mouth have had a rather messy adolescence - but thankfully the show itself has had far fewer growing pains, delivering four acclaimed seasons with a fifth now on the way.


The show was renewed for a whopping three more seasons - as well as a spin-off - after the release of season three, so there's plenty more amusingly absurd tales of teenage angst to come.

Thanks to Netflix's big TUDUM event, we finally have a release date for season five - and it's very soon.

Here's everything you need to know about Big Mouth season five.

Big Mouth season 5 release date

The streaming giant has loyally provided fans with a new series per year since its 2017 birth, and this is not about to change for season five.

Big Mouth's fifth season will arrive on Friday 5th November 2021 - less than a year after season four debuted in December 2020.

The release date was revealed at Netflix's big TUDUM event in September 2021, and arrives on an appropriate month as Big Mouth season five is set to cover events from "No Nut November" up until the New Year - meaning there may well be a Christmas special similar to previous episodes based on Valentine's Day and Halloween.

Big Mouth cast

Thankfully, we didn’t have to stomach a teary death of a character in season four, so we expect to see all the main cast in season five. The main case includes:

  • Nick Birch (along with Maury, Coach Steve, Lola and Rick) played by Nick Kroll
  • Andrew Glouberman (and Grandpa Andrew) played by John Mulaney
  • Jessi Glaser played by Jessi Klein
  • Jay B (along with Socrates and Guy B) played by Jason Mantzoukas
  • Missy played by Ayo Edebiri
  • Devon played by Jak Knight
  • Connie (along with Diane, Bath Mat, Ghost of Elizabeth Taylor, Ghost of Whitney Houston) played by Maya Rudolph
  • Matthew played by Andrew Rannells.

They'll also be some new guest stars this season, and in true Big Mouth style they will not be voicing humans but lovebugs and hate worms - the latest anthropomorphic representation of emotions that will teach the characters some life lessons.

Modern Love star Brandon Kyle Goodman will be joining as Nick's lovebug Walter who will be encouraging him to pursue Jessi, who has her own lovebug called Sonya played by King of the Hill's Pamela Adlon. Missy, on the other hand, will receive a hate worm called Rochelle, voiced by Hustlers actress Keke Palmer.

Goodman, Adlon and Palmer are also set to star in Human Resources, the long-gestating Big Mouth spin-off that is set in the world of the Hormone Monsters and the other creatures that manage human life.

More like this

Big Mouth season 5 trailer

Sadly no trailer just yet, but we'll update this page as soon as we can with one. Expect a trailer in October in the weeks leading up to the season's release date.

What will happen in Big Mouth season 5?

Though the sky’s the limit with an animated series like Big Mouth, it's kept relatively grounded as the main characters are in year eight at Bridgeton Middle School in Westchester Country.

Romances between Jessi & Nick, Jay & Lola and Missy & Devon have been the main drivers of the overall plot. We wonder how their relationships will progress or regress as they inch closer to end of middle school.

Matthew recently came out as gay, something his mum found difficult to accept. Season five will no doubt continue to explore that sensitive theme.

As shown in the poster, this season's overarching theme however will be love and hate. Following in the footsteps of the Hormone Monsters, the Shame Wizard and the anxiety mosquitoes, the theme will quite literally be represented onscreen by lovebugs and hate worms, shapeshifting creatures that amplify each character's feelings of - you guessed it - love or hate respectively.

Nick's lovebug Walter will prompt him to ask out Jessi once more, but her public rejection sees Walter transform into a hate worm and lead Nick down a dark, spiteful path. Jessi's rejection of Nick comes just as she is getting closer to Ali - prompting her and new lovebug Sonya to ponder whether she likes Ali more than a friend.

Jenny Slate voices Missy in Big Mouth

However Jessi's closeness with Ali inspires more than just jealousy in Missy - but also leads to the arrival of her own hate worm Rochelle, sending Missy on a similarly bitter journey to Nick.

There will be more than just ongoing spirals of love and hate this season though - as co-creator Mark Levin said at a USC Comedy Festival panel that the fifth instalment will “explore a little bit more about kids advocating and becoming political.”

However fellow co-creator Jennifer Flackett added that the show's lengthy production time makes topical comedy tricky, so any political themes would have to be rather broad.

“It takes us a long time to make a season, so topical humour is really, really hard,” Flackett said. “You can do something about political identity, like ‘I’m a Republican, I’m a Democrat, I’m a whatever,’ but I don’t think we could do anything [more specific]. Because we want the world to feel somewhat timeless, anyway.”


Big Mouth season five will be released on Friday 5th November 2021. Want something else to watch? Check out our full TV Guide or read our guides to the best series on Netflix and the best movies on Netflix.