Former EastEnders star John Partridge is set to star as Dr Hannibal Lecter, one of the most famous fictional serial killers, in a stage adaptation of Silence of the Lambs.

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The play, which has been adapted by Gina Gionfriddo from Thomas Harris's book of the same name, will open at Curve Theatre, Leicester, where it will run from 1 to 15 August 2026 before touring across the UK and Ireland.

The official synopsis for the production reads: "When FBI trainee Clarice Starling is sent to interview the psychiatrist and infamous murderer Hannibal Lecter, it’s hoped his brilliant mind will help catch the sadistic new serial killer, Buffalo Bill.

"Another girl is missing, and time is running out. But Dr Lecter has questions of his own, and now Clarice must decide: keep a safe distance, or let Hannibal ‘The Cannibal’ into her head?"

Partridge is best known for appearing as Christian Clarke in EastEnders, as well as his stage roles, which include The Rum Tum Tugger in Cats the musical and Hugo Battersby in Everybody’s Talking About Jamie.

John Partridge as Christian Clarke and Marc Elliott as Syed Masood in EastEnders.
John Partridge as Christian Clarke and Marc Elliott as Syed Masood in EastEnders. BBC PUBLIC SERVICE

The actor's casting as Dr Hannibal Lecter will see him follow in the footsteps of Anthony Hopkins, who played the character in the 2001 film of the same name, and Mads Mikkelsen, who appeared in the leading role in the hit TV series Hannibal.

Partridge said of his casting in a statement: "How often does an actor get to play a role that by simply saying the character’s name, it takes your breath away. It’s a huge honour, and I intend to savour every morsel of it!’’

Curve's artistic director, Nikolai Foster, who's serving as director, added: “Taking on a role like Hannibal Lecter requires real guts, tenacity and an appetite to confront the darkest depths of the human condition.

"Working with John on the role has been incredibly inspiring - his instincts are razor sharp - and there is no finer actor to bring to life Thomas Harris’s most chilling creation in our world premiere stage adaptation.”

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Head to our Going Out section for exclusive interviews with West End stars, like why Elaine Paige would never return to the West End and Rachel Zegler on the Evita balcony scene.

Authors

RadioTimes.com senior trends writer Molly Moss. She is sitting outside wearing a black top, holding a white teacup with a smily face on it to her mouth
Molly MossTrends Writer

Molly Moss is a Trends Writer for Radio Times, covering the latest trends across TV, film and more. She has an MA in Newspaper Journalism and has previously written for publications including The Guardian, The Times and The Sun Online.

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