The shocking story of Amanda Knox is headed to the small screen in a Disney Plus dramatisation, which features Nine Perfect Strangers and Tell Me Lies star Grace Van Patten in the title role.

Ad

Knox became the subject of major news coverage in 2007, at the age of just 20, while she was spending time in Italy as an exchange student from the University of Washington.

There, she was wrongly accused and later convicted of the murder of fellow student Meredith Kercher, serving four years in prison before being acquitted of the charges against her.

This drama miniseries recounts the dark saga, aiming to examine Knox's mental state during the traumatic ordeal and ask broader questions about the questionable media coverage and public reaction to the case.

If you're interested to know more, read on for all your essential details on The Twisted Tale of Amanda Knox.

The Twisted Tale of Amanda Knox release date

The Twisted Tale of Amanda Knox is available to stream on Disney Plus from Wednesday 20th August 2025.

Two episodes will drop on launch day, with the remaining six episodes scheduled to be rolled out weekly on Wednesdays on the streaming platform.

The Twisted Tale of Amanda Knox cast

John Hoogenakker, Sharon Horgan and Joe Lanza star in The Twisted Tale of Amanda Knox; their characters are sat behind a table at a press conference, with a number of microphones pointed in their direction
John Hoogenakker, Sharon Horgan and Joe Lanza star in The Twisted Tale of Amanda Knox. Disney / Andrea Miconi

Grace Van Patten leads the cast of The Twisted Tale of Amanda Knox, playing the titular figure, who was wrongfully convicted of murder in 2009.

Bad Sisters star Sharon Horgan also features as Amanda's mother, Edda Mellas, while John Hoogenakker (Dopesick), Giuseppe De Domenico (ZeroZeroZero) and Francesco Acquaroli (Fargo) are among the supporting cast.

Here's an overview of the key players in the Hulu and Disney Plus miniseries:

  • Grace Van Patten as Amanda Knox
  • Sharon Horgan as Edda Mellas
  • John Hoogenakker as Curt Knox
  • Giuseppe De Domenico as Raffaele Sollecito
  • Francesco Acquaroli as Giuliano Mignini
  • Roberta Mattei as Monica Napoleoni

What is The Twisted Tale of Amanda Knox about?

The key artwork for Hulu's The Twisted Tale of Amanda Knox, which sees the title character's face superimposed against an Italian skyline
The Twisted Tale of Amanda Knox. Hulu

The synopsis, courtesy of Hulu, reads: "The Twisted Tale of Amanda Knox follows the eponymous American college student, who arrives in Italy for her study abroad only to be wrongfully imprisoned for murder weeks later.

"The series traces Amanda's relentless fight to prove her innocence and reclaim her freedom, and examines why authorities and the world stood so firmly in judgment."

The Twisted Tale of Amanda Knox trailer

The trailer for The Twisted Tale of Amanda Knox was released in July 2025, three weeks before the series was set to drop on Disney Plus and Hulu. Tune in below for a glimpse at what's in store:

The Twisted Tale of Amanda Knox is available to stream on Disney Plus from Wednesday 20th August 2025.

Check out more of our Drama coverage or visit our TV Guide and Streaming Guide to find out what's on. For more TV recommendations and reviews, listen to The Radio Times Podcast.

Ad

Add The Twisted Tale of Amanda Knox to your watchlist on the Radio Times: What to Watch app – download now for daily TV recommendations, features and more.

Authors

David CraigSenior Drama Writer

David Craig is the Senior Drama Writer for Radio Times, covering the latest and greatest scripted drama and comedy across television and streaming. Previously, he worked at Starburst Magazine, presented The Winter King Podcast for ITVX and studied Journalism at the University of Sheffield.

Ad
Ad
Ad