ITV has cancelled Monroe, the medical drama starring James Nesbitt as a neurosurgeon, after two series.
The programme, created and written by Peter Bowker, debuted in March 2011 and averaged 5.7m viewers according to consolidated figures.
It returned last month, moving from Thursday to Monday nights and going up against BBC1 ratings monster New Tricks. It averaged 4m viewers.
Despite positive reviews for the second series, ITV has confirmed that Monroe, which co-starred Sarah Parish, Tom Riley and Neil Pearson, will not return for a third.
“It has been a fantastic series, which we have been proud to have on the channel," a spokesperson for ITV said, "but continuing to refresh our slate is an important part of the creative process for ITV Drama.”