Cavanaugh voiced characters in dozens of TV shows and films, with other credits including Marty Sherman in The Critic, Bunny in The Powerpuff Girls and parts in Darkwing Duck, the Aladdin TV series and The Wild Thornberrys.
In 1995, Cavanaugh gave her voice to the titular character in the hit film Babe, about a talking pig who becomes an unlikely sheep-herding champion.
She also played a variety of on-screen roles, including guest appearances on E.R., Everybody Loves Raymond, Wings, and The X-Files. She may be perhaps most recognised in person as Mrs. Remo in Jerry Maguire.
When Cavanaugh retired from acting in 2001 in order to spend more time with her family, Nancy Cartwright – who voices Bart Simpson – took over her Rugrats role.
The actress died on December 22nd, her family have announced. The cause of death has not yet been released.
Watch Cavanaugh as Rugrats’ Chuckie below: