In-ku (HAN Seok-kyu) is a neighborhood pharmacist with a good job and great personality. But for In-ku, marriage is nothing short of an unattainable dream, as long as his mentally handicapped brother In-seob (LEE Han-ewi) remains his responsibility. Hye-ran (KIM Ji-soo) moves into In-ku's neighborhood. She is a designer who copies the fashion lines of luxury design houses. Hye-ran is pretty and sophisticated, but for the past 5 years, she has been working to pay back the US$ 500,000 debt that her father racked up before his death. Depressed over the news of his ex-girlfriend's plans for a wedding, In-ku sits down to a couple of beers. Just then, Hye-ran walks into his drugstore, asking for a sleeping pill to help her go to sleep. Instead of the pill, In-ku hands over a can of beer. The mood turns friendly over the cans of beer, and slowly, the two begin to develop feelings for each other. And they find themselves going down the road neither of them thought they will ever be on again - the path to a relationship. They go to the movies together, they take trips together, and they learn to laugh again together. However, as their love grows, so do their burdens. When his mother's sudden death leaves In-ku alone to take care of his sick brother and when Hye-ran's pregnant sister threatens to get an abortion and call off the wedding, In-ku and Hye-ran are forced to give up the love they both worked so hard at.