Sienna's cervical cancer story has been confirmed as part of a new Hollyoaks trailer that spotlights all the upcoming drama on the C4 soap.
The shock medical news looks set to rock Sienna's world as she has to decide what would be the safest course of action to take, both for her and the unborn twins she's expecting with Warren.
Other plot highlights include the return of Luke and Mandy, plus a batch of episodes filmed in location that will see the introduction of new hunk Brody.
The long-running Who Killed Amy? whodunnit also continues as Lucas sends shockwaves through the village by telling his Auntie Tegan that somebody else was in the flat on the night Amy died after Ste had left. And then comes the news that the date of Ste's trial has been set for 4 September...
You can watch all the action below: